How is the structure of a protein related to its function?

A: Physical agitationHeatpH changes

B: Vitamin C is a critical co-factor for the function of two enzymes involved in making collagen proteins and stabilizing the collagen fibers.Without the enzymes, no hydroxyl groups will be put on the amino acids of collagen and it will become very weak

C: Denaturation - destroys protein functioncannot return to original shape

D: Protein shape in inextricably tied to its proper function. The final shape and components of proteins are essentially important to their function